Fetal Risk

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atezolizumab (FDA-USA)

Based on its mechanism of action, Atezolizumab can cause fetal harm when administered to a pregnant woman. There are no available data on the use of Atezolizumab in pregnant women. Animal studies have demonstrated that inhibition of the PD-L1/PD-1 pathway can lead to increased risk of immune-related rejection of the developing fetus resulting in fetal death. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, advise the patient of the potential risk to a fetus.